A Method to Address Differential Bias in Genotyping in Large-Scale Association Studies
نویسندگان
چکیده
منابع مشابه
A Method to Address Differential Bias in Genotyping in Large-Scale Association Studies
In a previous paper we have shown that, when DNA samples for cases and controls are prepared in different laboratories prior to high-throughput genotyping, scoring inaccuracies can lead to differential misclassification and, consequently, to increased false-positive rates. Different DNA sourcing is often unavoidable in large-scale disease association studies of multiple case and control sets. H...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2007
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.0030074